воскресенье, 2 декабря 2012 г.

M507/P259 Gypsy SNP?

Not so long ago M507/P259 fully entered into the category of private SNPs. But new scientific article(Ancestral modal Y-STR haplotype shared among Romani and South Indian populations) has allowed a new look at this SNP.

In our dataset, the I1c-P259 sub-clade was found to comprise all I chromosomes in the Roma from Bogojevo (8%) and about 1/3 of those in Belgrade (4.5%), yet this sub-haplogroup is completely absent from the general population of Serbia (Regueiro et al., 2012).

The predominantly European haplogroup I-M258, on the other hand, which has two foci of frequencies in northern Europe around Scandinavia (I1) and in the Balkan Peninsula (I2) (Rootsi et al., 2004), supports genetic admixture with host populations following their arrival in the Balkans. It is interesting to note that the I1c-P259 sub-clade, which comprises all "I" chromosomes in the Bogojevo population and 4.5% of patrilineages in the Roma from Belgrade, is absent from the general population of Serbia (Regueiro et al., 2012). In addition, the most common I1c-P259 16 loci-haplotype in our Roma collections (DYS19*14, DYS385*14-14, DYS389I*12, DYS389II*28, DYS390*22, DYS391*10, DYS392*11, DYS393*13, DYS437*16, DYS438*10, DYS439*12, DYS448*20, DYS456*14, DYS458*15, DYS635*22, GATA H4*20) is also the most frequently observed Y-STR profile among the Romani from Portugal and Bulgaria (Gusmão et al., 2008). These findings may indicate that the Belgrade and Bogojevo Roma were likely recipients of gene flow from autochthonous European populations prior to their entrance into Serbia.


The database FTDNA as aware of only one case of P259+


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