Показаны сообщения с ярлыком M507. Показать все сообщения
Показаны сообщения с ярлыком M507. Показать все сообщения
воскресенье, 23 ноября 2014 г.
суббота, 22 ноября 2014 г.
Gypsy I1
Genetic Structure of the Paternal Lineage of the Roma People Horolma Pamjav et al.
Haplogroups I1-M253 and I2a-P37.2. Twenty-two haplotypes from the five Roma groups and twelve from the Iberian Roma were included in the network of haplogroup I1-M253 (Fig. 1F). The modal haplotype was shared by all six Roma groups, while most Iberian haplotypes lay within two steps of the modal haplotype (Fig. 1F).
Haplogroups I1-M253 and I2a-P37.2. Twenty-two haplotypes from the five Roma groups and twelve from the Iberian Roma were included in the network of haplogroup I1-M253 (Fig. 1F). The modal haplotype was shared by all six Roma groups, while most Iberian haplotypes lay within two steps of the modal haplotype (Fig. 1F).
Haplogroup I (M170) is widespread over Europe but virtually absent elsewhere, including the Near East, suggesting that it arose in Europe (Rootsi et al., 2004). I1-M253 chromosomes were detected at relatively high frequencies in all six Roma groups compared, and 61.8% of these males share a modal haplotype (Fig. 1F), suggesting a common origin of the Roma as well. According to Gusma˜o et al. (2008), the I1-M253 marker occurred at different proportions in Roma groups compared to their host populations, but can be explained by genetic drift.
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воскресенье, 2 декабря 2012 г.
M507/P259 Gypsy SNP?
Not so long ago M507/P259 fully entered into the category of private SNPs. But new scientific article(Ancestral modal Y-STR haplotype shared among Romani and South Indian populations) has allowed a new look at this SNP.
In our dataset, the I1c-P259 sub-clade was found to comprise all I chromosomes in the Roma from Bogojevo (8%) and about 1/3 of those in Belgrade (4.5%), yet this sub-haplogroup is completely absent from the general population of Serbia (Regueiro et al., 2012).
The predominantly European haplogroup I-M258, on the other hand, which has two foci of frequencies in northern Europe around Scandinavia (I1) and in the Balkan Peninsula (I2) (Rootsi et al., 2004), supports genetic admixture with host populations following their arrival in the Balkans. It is interesting to note that the I1c-P259 sub-clade, which comprises all "I" chromosomes in the Bogojevo population and 4.5% of patrilineages in the Roma from Belgrade, is absent from the general population of Serbia (Regueiro et al., 2012). In addition, the most common I1c-P259 16 loci-haplotype in our Roma collections (DYS19*14, DYS385*14-14, DYS389I*12, DYS389II*28, DYS390*22, DYS391*10, DYS392*11, DYS393*13, DYS437*16, DYS438*10, DYS439*12, DYS448*20, DYS456*14, DYS458*15, DYS635*22, GATA H4*20) is also the most frequently observed Y-STR profile among the Romani from Portugal and Bulgaria (Gusmão et al., 2008). These findings may indicate that the Belgrade and Bogojevo Roma were likely recipients of gene flow from autochthonous European populations prior to their entrance into Serbia.
The database FTDNA as aware of only one case of P259+
In our dataset, the I1c-P259 sub-clade was found to comprise all I chromosomes in the Roma from Bogojevo (8%) and about 1/3 of those in Belgrade (4.5%), yet this sub-haplogroup is completely absent from the general population of Serbia (Regueiro et al., 2012).
The predominantly European haplogroup I-M258, on the other hand, which has two foci of frequencies in northern Europe around Scandinavia (I1) and in the Balkan Peninsula (I2) (Rootsi et al., 2004), supports genetic admixture with host populations following their arrival in the Balkans. It is interesting to note that the I1c-P259 sub-clade, which comprises all "I" chromosomes in the Bogojevo population and 4.5% of patrilineages in the Roma from Belgrade, is absent from the general population of Serbia (Regueiro et al., 2012). In addition, the most common I1c-P259 16 loci-haplotype in our Roma collections (DYS19*14, DYS385*14-14, DYS389I*12, DYS389II*28, DYS390*22, DYS391*10, DYS392*11, DYS393*13, DYS437*16, DYS438*10, DYS439*12, DYS448*20, DYS456*14, DYS458*15, DYS635*22, GATA H4*20) is also the most frequently observed Y-STR profile among the Romani from Portugal and Bulgaria (Gusmão et al., 2008). These findings may indicate that the Belgrade and Bogojevo Roma were likely recipients of gene flow from autochthonous European populations prior to their entrance into Serbia.
The database FTDNA as aware of only one case of P259+
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